13 NONCLINICAL TOXICOLOGY

US residents can call 1-800-222-1222. Canada residents can call 1-844-764-7669.

Pregnancy & Lactation

To treat erectile dysfunction-ED, take this drug by mouth as directed by your doctor, usually as needed. Take sildenafil at least 30 minutes, but no more than 4 hours, before sexual activity (1 hour before works best). This medication may take longer to start working if you take it with a high-fat meal. Do not take more than once daily as needed. The dosage is based on your medical condition, response to treatment, and other medications you may be taking.

Usual Pediatric Dose for:

Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Tell your doctor if your condition does not get better. Dizziness, headache, flushing, or stomach upset may occur. Vision changes such as increased sensitivity to light, blurred vision, or trouble telling blue and green colors apart may also occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

How sildenafil is used

To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Sexual activity may put extra strain on your heart, especially if you have heart problems. If you have heart problems and experience any of these serious side effects while having sex, stop and get medical help right away: Rarely, sudden decreased vision, or even permanent blindness, may occur in one or both eyes (NAION). Symptoms of overdose may include: severe dizziness, fainting, painful/prolonged erection.

Do not share this medication with others. Store at room temperature away from light and moisture.

2.5 Dosage Adjustments in Special Populations

Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness or clear vision until you can do it safely. Talk to your doctor if you are using marijuana (cannabis). Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). During pregnancy, sildenafil should be used only when clearly needed.

Pulmonary Arterial Hypertension

Since high blood pressure in the lungs is a serious condition that can harm both a pregnant woman and her unborn baby, do not stop taking this medication unless directed by your doctor. If you are planning pregnancy, become pregnant, or think you may be pregnant, discuss with your doctor right away the benefits and risks of using this medication during pregnancy. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist.

Related treatment guides

Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug are: Sildenafil can cause a serious drop in your blood pressure when used with nitrates. A serious drop in blood pressure can lead to dizziness, fainting, and rarely heart attack or stroke. Do not use sildenafil with any of the following: certain drugs used to treat chest pain/angina (nitrates such as nitroglycerin, isosorbide) recreational drugs called "poppers" containing amyl or butyl nitrite If you are also taking an alpha blocker medication (such as doxazosin, tamsulosin) to treat an enlarged prostate/BPH or high blood pressure, your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may start treatment with a lower dose of sildenafil to minimize your risk of low blood pressure. Keep all medications away from children and pets.

• Sildenafil 100 mg is not a cure for erectile dysfunction but helps temporarily.
• Lifestyle changes like exercise and diet can enhance treatment effectiveness.
• Open communication with a partner can improve the sexual experience and treatment satisfaction.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so.

Properly discard this product when it is expired or no longer needed.

What other drugs will affect sildenafil?

If this serious problem occurs, stop taking sildenafil and get medical help right away. You have a slightly greater chance of developing NAION if you have heart disease, diabetes, high cholesterol, certain other eye problems ("crowded disk"), high blood pressure, if you are over 50, or if you smoke. Rarely, a sudden decrease or loss of hearing, sometimes with ringing in the ears and dizziness, may occur. Stop taking sildenafil and get medical help right away if these effects occur. Rarely, males may have a painful or prolonged erection lasting 4 or more hours.

Allergy warning

If this occurs, stop using this drug and get medical help right away, or permanent problems could occur. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat) This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. You may report side effects to FDA at 1-800-FDA-1088 or at In Canada - Call your doctor for medical advice about side effects.

Oral Administration

You may report side effects to Health Canada at 1-866-234-2345. Before taking sildenafil, tell your doctor or pharmacist if you are sildenafil tablets lp 100 mg allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart problems (such as heart attack or life-threatening irregular heartbeat in the past 6 months, chest pain/angina, heart failure) penis conditions (such as angulation, fibrosis/scarring, Peyronie's disease) conditions that may increase the risk of priapism (such as sickle cell anemia, leukemia, multiple myeloma) eye problems (such as retinitis pigmentosa, sudden decreased vision, NAION) This drug may make you dizzy or cause vision problems. Consult your pharmacist or local waste disposal company.

• Female sexual arousal disorder is not treated with sildenafil 100 mg.
• The medication is intended for adult male patients only.
• Always obtain sildenafil from reputable pharmacies to avoid counterfeit drugs.

HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product.

This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional.

5.3 Effects on the Eye

Use this page to review package-level identifiers before comparing related family pages or starting a quote review. Click a tag to refine the catalog view around this product reference. Use official labeling and directory references to confirm presentation details while your team reviews the PRN catalog entry and related sourcing paths. These nearby package-level pages can help healthcare teams compare related packaging or presentation differences inside the same product-NDC family. Sildenafil Citrate 100 mg / 1 Tablet 60 Tablet, NDC 80425-0503-02, is a Advanced Rx of Tennessee, LLC 100 mg / 1 tablet presentation packaged as 60 Tablet.

Ajustements de doses

Possible 10-digit display formats: 80425-503-02 (8042550302), 80425-0503-2 (8042505032) Multiple 10-digit display-format aliases can map to the same stored 11-digit billing NDC, so these are shown as search aliases rather than a single asserted package format. Other package sizes in this family: 30 Tablet, 90 Tablet Compare related presentations: Sildenafil Citrate 100 mg / 1 Tablet 30 Tablet, Sildenafil Citrate 100 mg / 1 Tablet 90 Tablet Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction-ED). In combination with sexual stimulation, sildenafil works by increasing blood flow to the penis to help a person get and keep an erection. This drug does not protect against sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis). Using an effective barrier method (latex or polyurethane condom/dental dams) during sexual activity will help to decrease your risk of infection.

Mécanisme d'action

This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Sildenafil is also available in other brands and strengths for high blood pressure in the lungs (pulmonary hypertension). Read the Patient Information Leaflet if available from your pharmacist before you start taking sildenafil and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Always ask your health care professional for complete information about this product and your specific health needs. Selected from NATIONAL DRUG DATA FILE (NDDF) data included with permission and copyrighted by First Databank, Inc., 2019.

This copyrighted material has been downloaded from a licensed data provider. The above information is intended to supplement, not substitute for, the expertise and judgment of your health care professional.

Renal Dose Adjustments

Other medications can affect the removal of sildenafil from your body, which may affect how sildenafil works. Examples include azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as clarithromycin, erythromycin), mifepristone, rifampin, ritonavir, among others. Do not take this medication with any other product that contains sildenafil or other similar medications for erectile dysfunction-ED or pulmonary hypertension (such as tadalafil, vardenafil). If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment. take any medicines called nitrates, often prescribed for chest pain, or guanylate cyclase stimulators like Adempas® (riociguat) for pulmonary hypertension.